Through the time, a large variety of substances and procedures have been used as protective agents in lesions characterized by skin loss. From the application of fresh meat and honey, as reported in the Ebers Papyrus of 1500 B.C., to the current autografts of cultured skin, diverse materials were used, such as: autologous grafts, sulfonamide films, plastics and porcine xenografts. Various procedures were also employed in the treatment of burns and cutaneous abrasions in general, among them, closed or open dressings, with or without topical drugs.¹

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